The answer is a simple no. Isotherm Insulation is a dust free and allergy Free insulation.
Polyester is a B/B 1/1 fire rated insulation so it is ideal for homes.
The 145mm Isotherm is the SANS Compliant insulation with an installed R-value 3.76.
Sadly as of 2020 Isotherm is no longer SABS Approved.